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Inclusion criteria histologically confirmed diagnosis of colorectal carcinoma with kras g12c mutation in tumor tissue prior receipt of 1st line treatment in advanced crc with a fluoropyrimidine based chemotherapy regimen containing either oxaliplatin or irinotecan and radiographically documented progression of disease on or after treatment.

This phase ii trial studies nivolumab and ipilimumab in treating patients with rare tumors immunotherapy with monoclonal antibodies such as nivolumab and ipilimumab may help the bodys immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread.

Millard henry clinic 1 skyline dr russellville ar 7 14 1997 hematology oncology association of ne pa henry ford hospital 2799 w grand blvd detroit mi.